In addition, sphere formation assays showed that Foxg1 cKD in Lgr5 progenitor cells did not significantly alter their sphere formation capacity, and the findings suggest that Foxg1 cKD may directly trans-differentiate supporting cells and progenitor cells by inducing This study provides new evidence for the role of Foxg1 in regulating hair cell regeneration from supporting cells and progenitor cells in the neonatal mouse cochlea (Zhang et al., 2020). Here, FOXG1 is linked to chronic kidney disease.