ACE2 and infection: As shown in Figures 1C,D, LCB1 potently inhibited infections of the WT and D614G pseudoviruses with mean IC50 values of 0.191 and of 0.062 nM, respectively, on 293T/ACE2 cells and of 0.22 and 0.073 nM, respectively, on Huh-7 cells.