Sturm et al. [46] thought the expression of TTF-1 and 34βE12 may distinguish LCNEC from basal-like carcinoma, and basal-like carcinoma could be excluded when TTF-1 was expressed, while the presence of 34βE12 expression could exclude LCNEC. The gene discussed is TTF1; the disease is large cell neuroendocrine carcinoma.