The typical method of “oxidation therapy” is to deliver ROS-generating agents to cancer cells directly, including glucose oxidase (GOx), catalase (CAT), methyl quinone (MQ) and cinnamaldehyde (CA) (Noh et al., 2015; Zhen et al., 2018; Fu et al., 2019; Xu et al., 2021). Here, CAT is linked to cancer.