YcDNA detection was associated with elevated concentrations of MMP-2 (β = 0.419; CI 0.084, 0.753; P = 0.015), and TIMP-4 (β = 0.328; CI 0.042, 0.614; P = 0.025; Figure 1B) after adjusting for age, any STI, Nugent Score, the number of vaginal sex acts in the past 30 days, inflammation status, and randomization arm. The gene discussed is MMP2; the disease is sexually transmitted disease.