INS and infection: Genetic analysis identified a heterozygous GOF mutation (c.866A > G, p.Y289C) in <i>STAT1</i>.<h4>Results</h4>Various medicines were given to the boy during the follow-up, including insulin to keep blood glucose stable, intravenous immunoglobulin and antifungal agents for recurrent infections, and antituberculosis drugs (isoniazid, rifampicin) to combat tuberculosis infection.