demonstrated that all circulating MDSC subsets (CD11b+CD33+CD14−CD34+HLA-DR− or immature MDSC, CD11b+CD33+CD14−HLA-DR− or G-MDSC, CD14+HLA-DRlow/− or M-MDSC) were increased in HL patients compared to normal subjects. This evidence concerns the gene ITGAM and Hodgkins lymphoma.