Furthermore, lower expression of CDK7, AKT1, PARP1 (p < 0.1), CCND2 (cyclin D2), CDK2, CDK4, BIRC5 (survivin), PCNA and CDH2 (N-cadherin) (p < 0.005) have been shown to result in longer median survival of patients with mesothelioma (Supplementary Figure S6). This evidence concerns the gene CDK4 and mesothelioma.