MTT assay demonstrated that the IC50 value of DDP was decreased after transfected with si-circ-LIMK1#1 in A549/DDP and H1975/DDP cells (Figure 2b and c), indicating that circ-LIMK1 knockdown enhanced DDP sensitivity in DDP-resistant lung adenocarcinoma cells. Here, LIMK1 is linked to lung adenocarcinoma.