In addition, RT-qPCR analysis of the RNA level of HMGA1 showed that HMGA1 expression was up-regulated in tumor tissues compared with normal tissues (n = 56/group) (Figure 5d), the expression of HMGA1 was boosted in resistant tumor tissues (n = 37) compared with sensitive tumor tissues (n = 19) (Figure 5e). Here, HMGA1 is linked to neoplasm.