Previous investigations of the interactions between endometriosis risk SNPs in the 1p36.12 locus and candidate target genes using chromosome conformation capture (3C) in Ishikawa cell lines suggest that endometriosis risk SNPs interact with the promoters of both LINC00339 and CDC42. Subsequent luciferase reporter assays suggested the risk SNP rs12038474 was located in a transcriptional silencer for CDC42 and the risk allele increases expression of CDC42 in blood (93). Here, CDC42 is linked to endometriosis.