c-Myc is involved in the development of HCC, and almost 30% of human HCC samples show c-Myc gene amplification, which is correlated with protein expression; HBV, HCV, and aflatoxin, the main risk factors of HCC, have also been reported to induce overexpression of c-Myc (Xu et al., 2019). Here, MYC is linked to hepatocellular carcinoma.