TNF and hemorrhage: The results showed that there was no significant difference in gender, admission time, blood collection time, initial SBP, initial DBP, hypertension, current smoking, atrial fibrillation, and hemorrhage site between ICH patients with and without early neurological deterioration, but age, the admission NIHSS score, hematoma volume, WBC, and the levels of serum CRP, TNF-α, and IL-12 in ICH patients with early neurological deterioration were significantly higher than those in ICH patients without early neurological deterioration (Table 3).