NME7 gene knockdown causes primary ciliary dyskinesia (Šedová et al., 2021), MRPS31 gene deletion causes mitochondrial deregulation and the aggression of hepatocellular carcinoma (Min et al., 2021), and TPM1 gene knockdown causes early embryonic death (Ma et al., 2021). The gene discussed is MRPS31; the disease is primary ciliary dyskinesia.