CHEK2 and posterior cortical atrophy: The most common pathogenic germline variants involved in PCa include BReast CAncer gene 1 (BRCA1), BReast CAncer gene 2 (BRCA2), Homeobox Protein Hox-B13 (HoxB13), and Checkpoint Kinase 2 (CHEK2) (Wang et al., 2018).