Furthermore, to study the genomic alterations associated with race, the frequencies of somatic alterations in a cohort of AA and EA PCa patients were compared by Koga et al. Focal deletions in ETS Variant Transcription Factor 3 (ETV3), His-tone-lysine N-methyltransferase 2D (KMT2D) truncations, mutations in Zinc finger homeobox 3 (ZFHX3), and Cyclin D1 (CCND1) amplifications in early-stage PCa were more abundant in AA patients. This evidence concerns the gene ZHX3 and posterior cortical atrophy.