This strategy was previously successful in the identification of two novel PCD-loci CCDC103 and LRRC6 genes in UK-Pakistani populations (Panizzi et al., 2012; Zariwala et al., 2013) and CCNO causing oligocilia with situs solitus in a multiplex Kuwaiti family having four PCD individuals (Wallmeier et al., 2014). Here, DNAAF11 is linked to primary ciliary dyskinesia.