Chest X-ray; electrocardiogram; echocardiogram; electromyography; muscle magnetic resonance imaging; and nonspecific laboratory biomarkers including blood tests, such as creatine phosphokinase, lactate dehydrogenase (LDH), alanine transaminase (ALT), and aspartate transaminase (AST), and urine tests, such as glucose tetrasaccharide (HEX4), should be done in clinically suspected infants with Pompe disease [2, 16]. This evidence concerns the gene GPT and glycogen storage disease II.