BATF and cardiovascular disorder: Our xCell results showed that the number of macrophages in unstable plates increased significantly, indicating that the number and function of macrophages play a very important role in the progression of plaques, above studies indicate that BATF is mainly involved in the progression of cardiovascular disease as a regulatory factor of T cells, a single-cell sequencing database analysis showed that (https://panglaodb.se/index.html) BATF was also highly expressed in macrophages, so, it may be involved in regulating plaque instability or rupture.