In addition, FKBP13 was positively correlated with α-SMA and unfolded protein response markers, GRP78 and total XBP1, expression, suggesting that higher levels of FKBP13 are associated with increased clinical severity and idiopathic pulmonary fibrosis pathogenicity [66]. The gene discussed is ACTA1; the disease is idiopathic pulmonary fibrosis.