Furthermore, Staab-Weijnitz et al. [46] demonstrated that FK506-binding protein 10 (FKBP10), another member of immunophilin family, is upregulated in lung protein lysates from bleomycin-induced lung fibrosis mouse model that was also confirmed using the microarray analysis of 99 lung samples from idiopathic pulmonary fibrosis patients showing an upregulation of FKBP10 gene expression compared to control, and this upregulation was positively correlated with α-SMA levels, a myofibroblasts marker. This evidence concerns the gene ACTA1 and pulmonary fibrosis.