PCLAF and Behcet disease: A set of 15 serum EV-derived metabolites (chenodeoxycholic acid, lysoPE 18:0, lysoPE 14:0, N-acetylmethionine, 13-oxoODE, glycine, 1-naphthylacetic acid, 2-aminoethanesulfonic acid, D-2-aminobutyric acid, lysoPC 18:0, lysoPC 20:1, biopterin, phosphoric acid, glucosamine, and PAF C-16) was identified as a potential metabolite biomarker of BD that showed good to excellent performance in different sample sets [56].