Within CD4+ T cells, DEGs were significantly enriched in pathways such as cell cycle, DNA replication, homologous recombination, Fanconi anemia pathway, meiosis, nucleotide excision repair, base excision repair, and p53 signaling pathway (Fig. 7D), implying that the ATS signature has proliferative implications in CD4+ T cells. Here, TP53 is linked to Fanconi anemia.