In a second study, Scherberich et al. [16] investigated 132 patients with CKD (of them, only 53 were SLE patients), 190 adult blood donors and 443 children and adolescents; these authors pooled all the groups with different diseases that might potentially affect renal function, and identified a correlation of serum uromodulin with the eGFR adjusted by cystatin C (r = 0.842; p<0.001), serum creatinine (r = ‐0.802; p<0.001) and other parameters of renal function. This evidence concerns the gene CST3 and chronic kidney disease.