The second strength that should be pointed out is that the present study included the evaluation of serum uromodulin adjusted by the eGFR to identify its correlation with a wide spectrum of parameters of renal involvement and renal dysfunction, including proteinuria, creatinine clearance, and serum creatinine, which are commonly used in the clinic for detecting renal flares in SLE patients. This evidence concerns the gene UMOD and Abnormal renal physiology.