AFP and Decreased total leukocyte count: Consistent with our MS results, AFP abundance was elevated in P47 Sco1hep, P77 Coa5hep, and P64 Cox10hep plasma (Figure 4B), and its circulating levels were significantly higher in Sco1hep than Control plasma at P27 and continued to increase as the severity of the leukopenia worsened over time (Figure 4C).