ELISA results demonstrated that the levels of IL‐17, IL‐23, IL‐10, TGF‐β1, and IL‐6 were significantly higher in CRC patients with TNM stages of III–IV (Supporting Information: Figure S3C, p = .015; Supporting Information: Figure S3D, p = .033; Supporting Information: Figure S3E, p = .005; Supporting Information: Figure S3F, p = .019; Supporting Information: Figure S3G, p = .006). This evidence concerns the gene IL6 and colorectal carcinoma.