CASC3 and glioblastoma: To further evaluate the cytotoxic activity of the GO:BTZ complexes we initially utilized an orthotopic xenograft model of glioblastoma.[50] U87‐luc cells were injected into the striatum of athymic mice and tumors were allowed to establish for 14 days before mice received intratumoral injection of GOc or GO:BTZ (at 0.175 μg BTZ) (Figure 4A).