CD163 and neoplasm: Moreover, Tamura et al. found that patients with high T2W FLAIR hyperintensity (beyond 1400 mm3) had more CD163+ cells in the TC (Tamura, Ohara, Sasaki, Morimoto, Yoshida, et al., 2018), which are involved in invasiveness, tumor cell migration, angiogenesis, immune evasion, edema formation, and worse survival rate (Bette et al., 2018).