Reactive astrocytes express high levels of glial fibrillary acidic protein (GFAP) and support parenchymal infiltration and uncontrolled proliferation of glioma cells by expressing matrix metalloproteinase‐2 (MMP2) and secreting stromal cell–derived factor‐1 (SDF1), respectively (Barbero et al., 2002; Gagliano et al., 2009). This evidence concerns the gene GFAP and glioma.