F2 and blood coagulation disease: In the present study, we found that age ≥25 years old, coagulopathy, lower levels of hemoglobin (< 82.0 g/L) and aspartate aminotransferase (< 119 IU/L), higher levels of lactate dehydrogenase (≥687 IU/L), creatinine (≥118 μmol/L), and ferritin (>2,000 μg/L), and prolonged prothrombin time (≥17.1 s) might be independent risk factors for 90-day OS from diagnosis.