In a case control study of 705 patients, the odds of stroke were much higher within the first 6 months of ART compared to those who were treatment naïve (adjusted odds ratio 15.6), as well as in those with CD4 less than 200 cells/mm3 compared to those with CD4 greater than 500 cells/mm3 (adjusted odds ratio 12.9)9. Here, CD4 is linked to stroke disorder.