Apart from that, these findings provide a foundation for further demonstrating the variations in the IL-17 family genes are positively linked with susceptibility to cervical cancer, lung cancer, asthma, MS, RA, SpA, and highlight that the variants in IL-17 family genes might become a valuable genetic tool to investigate the pharmacological targeting potential of IL-17 family genes. This evidence concerns the gene IL17A and rheumatoid arthritis.