Circ_0000437 expression was positively correlated with TNM classification, differentiation degree, tumor size, and Barcelona Clinic Liver Cancer (BCLC) stage; hsa_circ_0003998 expression positively correlated with serum AFP level, tumor diameter, and microvascular invasion, whereas hsa_circ_0064428 expression was negatively correlated with patient’s survival, tumor size and metastasis. Here, AFP is linked to neoplasm.