We showed that the levels of selected biomarkers are significantly higher in HF patients with salivary gland dysfunction compared to those with normosalivation and healthy subjects (IL-1β, TNF-α, IL-7, IL-13, INF-γ, IL-12, IL-15, IL-5, IL-6, IL-9, IL-17, MCP-1/CCL-2, EOTAXIN/CCL11, RANTES/CCL5, GM-CSF, VEGF, FGF basic, PDFG-BB). This evidence concerns the gene IL5 and hydrops fetalis.