They identified commonly mutated genes that characterize pancreatic ductal adenocarcinomas (KRAS, TP53, SMAD4, and CDKN2A) and also identified two additional genes not previously described in human pancreatic ductal adenocarcinomas (KDM6A and PREX) [11-13]. The gene discussed is CDKN2A; the disease is pancreatic ductal adenocarcinoma.