LAG3 and nonpapillary renal cell carcinoma: In addition, the internal relationship between DBT expression in ccRCC and immune checkpoint genes was investigated on the TISIDB website, and a clear negative correlation was found between DBT and immunoinhibitors, such as CTLA4 (r = −0.326, p = 1.41e-14), TIGIT (r = −0.247, p = 7.88e-09), LAG3 (r = −0.349, p = 9.39e-17), and PDCD1 (r = −0.34, p = 7.81e-16) (Figures 8D,E).