A higher risk of developing PD has been linked to variants in a number of PARK-designated (SNCA, UCHL1, LRRK2, PARK 16, GAK) and a few additional genes (MAPT, GBA, NAT2, INOS2A, GAK, HLA-DRA, and APOE) (Postuma et al., 2015). This evidence concerns the gene UCHL1 and Parkinson disease.