RAB4A and lupus nephritis: In addition to these findings, it has recently been shown that mTORC1 activation in glomeruli is higher in participants with lupus nephritis than in participants with DMN (Mao et al., 2022), that ATG5 and ATG7 and the HRES-1/Rab4A are associated with the molecular pathogenesis of lupus, and genetically driven mTOR activation is associated with fulminant lupus nephritis (Caza et al., 2022).