In recent years, with the development of serological diagnostic markers, serum indicators such as procalcitonin (PCT) and C-reactive protein (CRP) have become more clinically accepted indicators to assess the status of infection, and their elevation can reflect the severity of the disease; the PCIS score is also the most objective, widely used, and effective score in China, which can effectively reflect the criticality of the child's condition and has a good predictive effect on the risk of death [5]. The gene discussed is CRP; the disease is infection.