According to the results of bubble chart, PI3K-Akt signaling pathway involved 34 (15.89%) potential therapeutic LBP targets, microRNAs in cancer and proteoglycans in cancer; Ras signaling pathway involved 23 (10.75%) potential therapeutic LBP targets; neuroactive ligand-receptor interaction involved 22 (10.28%) potential therapeutic LBP targets; prostate cancer, Rap1 signaling pathway, Alzheimer disease, and MAPK signaling pathway involved 20 (9.35%) potential therapeutic LBP targets and so on. This evidence concerns the gene AKT1 and early-onset autosomal dominant Alzheimer disease.