1.Allergic disease: any/specific IgE >0.7 kU/L2.Sensitization: any/food-specific/inhalant-specific IgE >0.7/>0.35 kU/L3.Doctor-diagnosed allergy ever: all/IgE-associated eczema, asthma, rhinitis or food allergy4.ISAAC-diagnosed allergic disease in last 12 M: allergic disease, specific IgE >0.7 kU/L, IgE-associated eczema, asthma and rhinitis. The gene discussed is IGHE; the disease is Eczematoid dermatitis.