The results of lncRNA and mRNA differential expression genes identified 963 differential lncRNAs and 537 differential mRNA, among which Shank3 and SYNE1 were related to the central nervous system [17, 18], lncZNRD1 was reported in cancer [19], and mfge8 was considered as a feasible biomarker for diagnosis and prognosis of liver cancer [20]. This evidence concerns the gene SHANK3 and cancer.