This study identified 13 genes (MIR570, MIR590, MIR4506, MIR4786, IL1RL1, RNASE2, CD163, ST6GALNAC3, SIGLEC9, VSIG4, NPTX2, BLM, TUBA3E) that were closely related to HF. The gene discussed is SIGLEC9; the disease is hydrops fetalis.