Sala et al., 2016 reviewed several miRNAs that play an essential role in HF, such as miR-18a-5p, miR-652–3p, and miR-126 (Wang and Cai, 2017). LncRNAs are essential regulators during cardiovascular development (Fan et al., 2018). Researchers found that lncRNA-Cancer Susceptibility Candidate 7 (CASC7) is involved in the progression of HF by regulating the expression of miR-30c, which is also a promising diagnostic-related gene for HF (Xu et al., 2020). In addition, the three RNA molecules are complexly interconnected (Song et al., 2016). Here, AGO2 is linked to hydrops fetalis.