For example, the presence of aconitase 2 (ACO2), IDH1, the subunit G of the IDH3 complex (IDH3G), oxoglutarate dehydrogenase (OGDH) subunit from the oxoglutarate dehydrogenase complex (OGDC) in the nucleus has been described using the human cervical cancer cells HeLa (Kafkia et al., 2022). This evidence concerns the gene ACO2 and cervical cancer.