After the adjustment of operating time and intraoperative hypotension, levels of IL-6 (Prep, POD1, POD2), IL-12 (POD1, POD2), IL-18 (POD1, POD2), and IL-8 (POD2) were found to be correlated with postoperative infection outcomes (p < 0.05). This evidence concerns the gene IL18 and infection.