CHI3L1, namely chitinase 3-like 1 protein, was a secretory glycoprotein which promoted tumor infiltration and migration in various neoplasms by elevating the expression levels of matrix metalloproteinase (MMPs) family genes (Studer et al., 2011; Fang and Jiang, 2016; Jin et al., 2019). The gene discussed is CHI3L1; the disease is neoplasm.