A decrease in the expression of the following genes was also observed in COVID-19-positive patients: RAPGEF1 (p = 0.0091), MAP2K1 (p = 0.038), CEBPB (p = 3.3 × 10−6), STAT6 (p = 0.041), JUN (p = 1.4 × 10−8), PRKACA (p = 0.021), and AKT1 (p = 1.3 × 10−6) (Supplementary Figure S4A). The gene discussed is RAPGEF1; the disease is COVID-19.