TPO and autoimmune disease: Recently, Vojdani et al. conducted an investigation aimed at studying the relationship between autoimmune target proteins and SARS-CoV-2 spike protein antibodies, the results of which proved that there were multiple tissue antigens that showed powerful reactions with the SARS-CoV-2 antibodies, such as transglutaminase 3, anti-extractable nuclear antigen, thyroid peroxidase, etc. [58], which indicated the fundamental role of cross-immune response in autoimmune diseases.