She had severe macrocytic anemia (Hb 5.8 [11.8–14.6 g/dL]); thrombocytopenia (Plt 7 [150–360 × 109/L]); conjugated hyperbilirubinemia, raised reticulocyte counts and LDH, low haptoglobin, hypocomplementemia, and mildly raised troponin I. No schistocytes were seen on the peripheral blood film. This evidence concerns the gene HP and Thrombocytopenia.