Finally, concerning the effector-memory B-lymphocytes (CD19+CD27+CD21−), a similar proportion was detected when comparing the COVID-19(−) and recovered COVID-19(+) participants in the same group (nonvaccinated, with the first vaccine dose, and with the second vaccine dose) and when comparing the samples from the second dose with the samples from the nonvaccinated. This evidence concerns the gene CD27 and COVID-19.