By Day 7, when animals began to succumb due to moribundity (near death, scores >14), there was universal evidence for infection from: virological data (plaque assay, qRT-PCR, sGP); gross abnormalities observed in multiple organs consistent with systemic infection; microscopic findings including inflammation, necrosis, fibrin, thrombosis, and hemorrhage noted in multiple organs; and other biomarkers commonly correlated with SUDV-induced disease including increased body temperature, elevated GGT, ALT, ALP, BA, BUN, CRP, and decreased ALB values. The gene discussed is CRP; the disease is infection.