Among the DCs subsets within tumours, having a large amount of cDC1 is beneficial, since they take up cancer antigens from tumours and migrate to lymph nodes, in which chemokine expressions, such as CXCL9, 10, and CCL5, in the tumour and intratumoural environment induce stronger T cell migration and cross-prime CD8+ T cells [268,269,270]. The gene discussed is MPPE1; the disease is neoplasm.