On the other hand, ROC analysis for the same four variables in the severe group of COVID-19 patients revealed that AUC were 0.844, 0.657, 0.765, 0.694 for IL-6, TXA2, NF-κB p50 and NF-κB p65 with sensitivities 100, 92, 74, and 70% and specificities of 68, 53, 74, and 60 %, respectively. The gene discussed is NFKB1; the disease is COVID-19.