In the moderate group of COVID-19 patients, ROC analysis indicated that AUC were 0.656, 0.843, 0.735, 0.806 for IL-6, TXA2, NF-κB p50 and NF-κB p65 with sensitivities of 100, 88, 80, and 80%, and with specificities of 50, 75, 56, and 67% respectively. This evidence concerns the gene IL6 and COVID-19.