BRCA1 and cancer: Because of these similarities within BRCA1-mutated breast cancer, we hypothesized that some neoantigens may be found recurrently across individuals with BRCA1 mutations and may be used as neoantigens for off-the-shelf cancer vaccines, both for therapeutic purposes for cases with somatic BRCA1 mutations, and for preventive purposes for those with germline BRCA1 mutations.